Medicantes

Metformina Clorhidrato

Metformina clorhidrato is an oral antidiabetic medication used to manage type 2 diabetes mellitus. It helps control blood sugar levels, especially in overweight patients, and is often the first-line treatment for type 2 diabetes.

Key Uses:
  • Type 2 diabetes mellitus (non-insulin-dependent)
  • May be used with insulin or other medications
  • Sometimes prescribed for polycystic ovary syndrome (PCOS) (off-label)
How It Works:

Metformin works by:

  • Reducing glucose production in the liver
  • Decreasing intestinal absorption of glucose
  • Improving insulin sensitivity
Dosage & Administration:
  • Taken orally, with meals to reduce stomach upset
  • Available in immediate-release and extended-release tablets
  • Usual starting dose: 500 mg once or twice daily, gradually increased
  • Maximum dose: 2000–2550 mg/day, depending on the formulation
Common Side Effects:
  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort
  • Metallic taste
Serious Side Effect (Rare):
  • Lactic acidosis – a rare but serious condition; seek medical help if experiencing weakness, difficulty breathing, or unusual muscle pain

Precautions:

  • Not for use in type 1 diabetes
  • Use with caution in kidney or liver impairment
  • Avoid alcohol
  • Monitor kidney function regularly
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